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Designs for Health

P-5-P is the pyridoxal-5-phosphate form of vitamin B6. Vitamin B6 occurs in three forms – pyridoxine hydrochloride, pyridoxal, and pyridoxamine – all of which must be converted into activated P-5-P by the liver. P-5-P is the bioactive form of vitamin B6 the body ultimately uses and requires for a wide range of biochemical processes critical for physical and mental health.

Vitamin B6 is found in animal and plant foods and is widely available in the food supply. However, some individuals have health challenges that may impair the body’s capacity to convert other forms of B6 into active P-5-P. Additionally, occasional periods of stress or illness may increase the body’s need for B6 above that which can reasonably be obtained from food. Elderly individuals, individuals who consume large amounts of alcohol, and individuals with suboptimal liver health may benefit from supplemental amounts of P-5-P. Some medications also interfere with B6 metabolism in the body.

P-5-P is necessary for the production of neurotransmitters that help support balanced moods, a positive mental outlook, and a healthy response to stress. These include gamma-aminobutyric acid (GABA – a calming neurotransmitter), the conversion of 5-HTP to serotonin (sometimes called the “feel good” neurotransmitter), and the conversion of L-DOPA into dopamine (a neurotransmitter involved in the “reward pathways” in the brain).

P-5-P is also a required cofactor for the enzyme that synthesizes heme, the iron-containing portion of hemo-globin, which is the molecule that carries oxygen in the blood. Therefore, P-5-P is crucial for maintaining healthy energy levels by facilitating the delivery of oxygen to tissues throughout the body. Additionally, P-5-P helps maintain healthy blood glucose levels by serving as a cofactor for enzymes that break down the body’s stored carbohydrates (glycogen) into glucose, as well as enzymes involved in generating glucose from amino acids—a process called gluconeogenesis. Another process that depends on adequate P-5-P is the conversion of homocysteine to the amino acid cysteine. (Elevated homocysteine may be a marker for compromised cardiovascular health.

Based on the many functions of P-5-P, this product may be beneficial for:

  • Supporting healthy blood glucose levels
  • Promoting a positive mental outlook
  • Supporting a balanced response to stress
  • Supporting a normal, healthy attitude during the menstrual cycle
  • Water retention

Serving Size: 1 Capsule
Amount Per Serving
Vitamin B-6 (Pyridoxal-5-Phosphate) 50mg

Other Ingredients: Microcrystalline cellulose‚ cellulose (capsule)‚ vegetable stearate.

Does not contain gluten‚ dairy‚ soy or GMOs.

As a dietary supplement, take one capsule per day, or as directed by your health care practitioner.

120 capsules

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353 reviews
Got Sick - Respiratory Specific
Catherine - San Francisco
Extra-Level Respiratory Support

Nourishing Lung tincture has been our go-to during the now-annual fire season, reducing the impacts of smoke & polluted air, and for providing overall respiratory support.
Got Sick-Respiratory Specific is a great addition for the onset of URIs and other respiratory distress, as it seems to act rapidly and deeply. It's also very effective in combination with Nourishing Lung. My husband was developing a URI following surgery, and before calling the Dr for antibiotics, he opted to try using both tinctures, together with Got Sick regular formula. Significant improvement occurred within 12 hours and he was able to clear it without medication. Highest recommendation.

Thank you for letting us know how these worked for you!

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Like the ease of the capsules. Also use the powder. Excellent way to add fiber and help digestive track. Definitely use it daily.

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Kim Metcalf
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Helps some when eating dairy or gluten on a occasional basis. Have purchased several bottles over the past few years.

Life saver!

Recommended to me by 2 Naturopaths. this product has helped me out of SIBO issues and also maintained my body's natural gastric process.
Whenever I have a flare up of digestive problems, this product, in combination with garlic and probiotics has helped me restore things without the torment of antibiotics, which destroy your gut lining. I highly recommend staying on an assigned regiment of Candibactin BR for a cure.

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